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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIMK2
All Species:
22.73
Human Site:
T375
Identified Species:
50
UniProt:
P53671
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53671
NP_005560.1
638
72232
T375
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
Chimpanzee
Pan troglodytes
XP_001148746
647
72505
K383
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852696
638
72125
T375
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
Cat
Felis silvestris
Mouse
Mus musculus
O54785
638
72184
T375
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
Rat
Rattus norvegicus
P53670
638
72183
T375
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506118
617
69519
T354
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
A
Chicken
Gallus gallus
P53666
642
72449
T375
E
T
Q
K
T
F
L
T
E
V
K
V
M
R
S
Frog
Xenopus laevis
O42565
615
69775
K358
E
T
Q
R
T
F
L
K
E
V
K
V
M
R
C
Zebra Danio
Brachydanio rerio
NP_001002651
651
74058
K381
E
T
Q
K
T
F
L
K
E
V
K
V
M
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IR79
1257
139286
K445
E
A
Q
R
N
F
I
K
E
V
A
V
L
R
L
Honey Bee
Apis mellifera
XP_396603
1027
115500
K367
E
A
Q
K
N
F
L
K
E
V
A
V
L
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.4
N.A.
95.4
N.A.
93
92.9
N.A.
86
85.9
52.8
65.7
N.A.
24.9
29.7
N.A.
N.A.
Protein Similarity:
100
70.6
N.A.
97.6
N.A.
96
96
N.A.
91.5
91.2
68.9
77.1
N.A.
34.2
41.8
N.A.
N.A.
P-Site Identity:
100
80
N.A.
100
N.A.
100
100
N.A.
93.3
100
80
93.3
N.A.
46.6
66.6
N.A.
N.A.
P-Site Similarity:
100
86.6
N.A.
100
N.A.
100
100
N.A.
100
100
86.6
93.3
N.A.
66.6
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
0
0
0
0
19
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
100
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
73
0
0
0
46
0
0
82
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
91
0
0
0
0
0
19
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
28
0
0
0
0
0
0
0
0
0
100
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% S
% Thr:
0
82
0
0
82
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
100
0
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _